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Corus CAD Patient Selection

The Corus CAD test is intended for use in patients who present with stable symptoms suggestive of obstructive CAD.

Typical symptoms suggestive of CAD may include:

  • Chest discomfort, tightness, pain, or pressure
  • Shortness of breath

Atypical symptoms suggestive of CAD may include:

  • Tightness or pressure in the throat, jaw, shoulder, abdomen, back, or arm
  • Squeezing, heaviness, or burning sensation in the upper body
  • Abdominal discomfort or fullness
  • Indigestion or heartburn
  • Nausea
  • Vomiting
  • Dizziness or light-headedness
  • Palpitations or awareness of heartbeat

(To be suggestive of obstructive CAD*, these atypical symptoms should be concurrent with at least one CAD risk factor. Some examples of CAD risk factors include high cholesterol, hypertension, family history, smoking, post-menopausal, morbid obesity, and known non-cardiac vascular disease.)

The Corus CAD test is NOT intended for patients who:

  • Have a history of obstructive CAD
  • Have had a prior myocardial infarction or revascularization procedure
  • Are diabetic
  • Are currently taking steroids, immunosuppressive agents, or chemotherapeutic agents

For a complete description of the intended use population for the Corus CAD test, please see the Corus CAD Intended Use Statement.

* Obstructive CAD is defined as at least one atherosclerotic plaque causing ≥50% luminal diameter stenosis in a major coronary artery (≥1.5 mm lumen diameter) as determined by invasive quantitative coronary angiography or coronary computed tomography angiography (≥2.0 mm lumen diameter).